In HIV-infected individuals receiving suppressive antiretroviral therapy, the virus persists indefinitely in a reservoir of latently infected cells.The proliferation of these cells may contribute to the stability of the reservoir and thus to the lifelong persistence of HIV-1 in infected individuals.Because the HIV-1 replication process is highly er
In EVERYONE LOTION COCONUT this paper, a new algorithm to improve the accuracy of estimating diameter at breast height (DBH) for tree trunks in forest areas is proposed.First, the information is collected by a two-dimensional terrestrial laser scanner (2DTLS), which emits laser pulses to generate a point cloud.After extraction and filtration, the l
Background Neonates undergo many uncomfortable, invasive minor procedures during their first hospital stay.Nonpharmacological interventions may provide valuable alternatives for pain relief in neonates during minor procedures.Objective To compare the analgesic effect of orally administered breast milk vs.non-nutritive sucking (NNS) in neonates who
Herpes simplex virus (HSV) establishes lifelong latent infection and can cause serious human disease, but current antiviral therapies target lytic but not latent infection.We screened for sgRNAs that cleave HSV-1 DNA sequences efficiently in vitro and used these sgRNAs to observe the first editing of quiescent HSV-1 DNA.The sgRNAs targeted lytic re
Abstract As silver nanowires (Ag NWs) are usually manufactured by chemical synthesis, a patterning process is needed to use them as functional devices.Pulsed laser ablation is a promising Ag NW patterning process because it is a simple and inexpensive procedure.However, this process has a disadvantage in that target materials are wasted owing to th